Imec has developed an organ-on-chip platform that combines imec’s high-density multi-electrode array (MEA)-chip with a microfluidic device. This new technology will allow the culture of cells in conditions that mimic human physiology as well as accurate cell reprogramming to grow complex tissue models. Another great advantage is that it is capable of performing multiple tests at the same time, consolidating itself as a powerful potential tool for cell interfacing applications. Growing organs on chip, personalized drug screening for disease modelling as well as for patient-derived cell-based therapies are some of the realities that will come hand in hand with this novel technology.
The INSERM Workshop focused on “Organ on Chip: understanding and mimicking living organisms for better treatment” took place in France in October 2018. Its main aim was to educate and spread knowledge about this technology. We are glad to announce that it was a success and it had a large influx of participants. Do you want to read more, click here.
The FET Flagship proposal ‘Health EU’ has been successfully submitted. This proposal is coordinated by Alexander Eggermont (Goustave Roussy), Adrian Ionescu (EPFL) and Albert van den Berg (UTwente). The ambitious unifying goal is empowering every citizen with a Human Avatar enabling access to comprehensive personalized healthcare, healthy lifestyle and disease prevention.
hDMT is member of the Strategic Board and coordinator of the Organ-on-Chip (OoC) pillar in this project with many partners of the European OoC network involved.
In total the Consortium consists of 110 partners, more than 75 stakeholders and hundreds of enthusiastic supporters across Europe. There is an International Advisory Board including 2 Nobel Laureates, several ex-Ministers of Health of EU countries and many international leaders and experts in Europe, USA and Canada. See https://www.health-eu.eu
In this paper, ORCHID partner CEA has demonstrated that organoid cultures in 3D matrices inside organ on chip micro devices are relevant models to mimic the complex in vivo environment that supports cell physiological and pathological behaviors. Read the full paper here.
The importance of spreading science to young people to create new vocations. Ignacio Ochoa (UNIZAR) talks about ORCHID with students from various institutes and schools in Zaragoza.
The abstract and poster on the ORCHID project, including the growing organ-on-chip network in Europe, were presented by hDMT at the EUROoC workshop in Stuttgart.
Organ-on-chip technology allows representing in vitro human organs and disease models in the context of human genetics as well as mimicking in vivo disease tissue environment leading to personalized medicine and reduction of animal experimentation in fields as critical as drug development or cancer. (more…)
23 May, 2018
On 23 May 2018 31 experts from 14 countries, representing academia, industry, regulatory bodies and medical centers, met in a welcoming atmosphere at Fraunhofer IGB in Stuttgart during a workshop of the ORCHID (Organ-on-Chip In Development) project. The purpose of this invitational Vision workshop was to define the ingredients of the European organ-on-chip roadmap. The workshop was organized by Janny van den Eijnden-van Raaij from hDMT (work package leader Roadmap) and chaired by Christine Mummery from LUMC (coordinator). (more…)
Leiden, The Netherlands
19 October, 2017
The ORCHID kick-off meeting took place at the Leiden University Medical Center in the Netherlands on October 19th 2017.
All partners of the ORCHID project presented their plans and discussed how to accelerate the societal and economic impact of Organ-on-Chip technology through coordinated action.